Particulate matters increase epithelial-mesenchymal transition and lung fibrosis through the ETS-1/NF-κB-dependent pathway in lung epithelial cells

Particulate matters increase epithelial-mesenchymal transition and lung fibrosis through the ETS-1/NF-κB-dependent pathway in lung epithelial cells

Abstract Background Particulate matters (PMs) in ambient air pollution are closely related to the incidence of respiratory diseases and decreased lung function. Our previous report demonstrated that PMs-induced oxidative stress increased the expression of proinflammatory intracellular adhesion molec...

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Bibliographic Details
Main Authors: Yu-Chen Chen, Tzu-Yi Chuang, Chen-Wei Liu, Chi-Wei Liu, Tzu-Lin Lee, Tsai-Chun Lai, Yuh-Lien Chen
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Particle and Fibre Toxicology
Subjects:
Particulate matters (PMs)
EMT
Fibronectin
ETS-1
Pulmonary fibrosis
Online Access:http://link.springer.com/article/10.1186/s12989-020-00373-z

Internet

http://link.springer.com/article/10.1186/s12989-020-00373-z

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