Proteomic Workflows for Biomarker Identification Using Mass Spectrometry — Technical and Statistical Considerations during Initial Discovery

Proteomic Workflows for Biomarker Identification Using Mass Spectrometry — Technical and Statistical Considerations during Initial Discovery

Identification of biomarkers capable of differentiating between pathophysiological states of an individual is a laudable goal in the field of proteomics. Protein biomarker discovery generally employs high throughput sample characterization by mass spectrometry (MS), being capable of identifying and...

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Bibliographic Details
Main Authors: Dennis J. Orton, Alan A. Doucette
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:Proteomes
Subjects:
biomarker discovery
experimental design
randomization
replication
high dimensional data
Online Access:http://www.mdpi.com/2227-7382/1/2/109

Internet

http://www.mdpi.com/2227-7382/1/2/109

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