DeepAtrophy: Teaching a neural network to detect progressive changes in longitudinal MRI of the hippocampal region in Alzheimer's disease

DeepAtrophy: Teaching a neural network to detect progressive changes in longitudinal MRI of the hippocampal region in Alzheimer's disease

Measures of change in hippocampal volume derived from longitudinal MRI are a well-studied biomarker of disease progression in Alzheimer's disease (AD) and are used in clinical trials to track therapeutic efficacy of disease-modifying treatments. However, longitudinal MRI change measures based o...

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Bibliographic Details
Main Authors: Mengjin Dong, Long Xie, Sandhitsu R. Das, Jiancong Wang, Laura E.M. Wisse, Robin deFlores, David A. Wolk, Paul A. Yushkevich
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:NeuroImage
Subjects:
Longitudinal analysis
T1-weighted MRI
Alzheimer's disease
Hippocampus area
Interscan interval
Disease progression
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811921007874

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http://www.sciencedirect.com/science/article/pii/S1053811921007874

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