6″-Debromohamacanthin A, a Bis (Indole) Alkaloid, Inhibits Angiogenesis by Targeting the VEGFR2-Mediated PI3K/AKT/mTOR Signaling Pathways

Hamacanthins, bis (indole) alkaloids, are found in a few marine sponges, including Spongosorites sp. Hamacanthins have been shown to possess cytotoxic, antibacterial and antifungal activities. However, the precise mechanism for the biological activities of hamacanthins has not yet been elucidated. I...

Full description

Bibliographic Details
Main Authors: Sang Kook Lee, Jongheon Shin, Oug Jae Cheong, Song Yi Bae, Gi Dae Kim
Format: Article
Language:English
Published: MDPI AG 2013-04-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/11/4/1087