Temporal expression profiling identifies pathways mediating effect of causal variant on phenotype.
Even with identification of multiple causal genetic variants for common human diseases, understanding the molecular processes mediating the causal variants' effect on the disease remains a challenge. This understanding is crucial for the development of therapeutic strategies to prevent and trea...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-06-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC4454590?pdf=render |