Expression of BRCA1-associated protein 1 in primary tumors and metastasis in an animal model of uveal melanoma

Expression of BRCA1-associated protein 1 in primary tumors and metastasis in an animal model of uveal melanoma

Background: Uveal melanoma (UM) is the most common primary intraocular tumor in adults. Despite successful local treatment, approximately 50% of these patients develop lethal metastatic disease. BRCA1-associated protein 1 (BAP1) encodes BAP1, which functions as a tumor suppressor. Inactivation by a...

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Bibliographic Details
Main Authors: Clara E Castro, Julia Valdemarin Burnier, Sabrina Bergeron, Jacqueline Coblentz, Ana Beatriz Dias, Miguel Noel Burnier
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:The Pan-American Journal of Ophthalmology
Subjects:
animal model
brca1-associated protein 1 mutation
immunohistochemistry
metastasis
uveal melanoma
Online Access:http://www.thepajo.org/article.asp?issn=2666-4909;year=2020;volume=2;issue=1;spage=26;epage=26;aulast=Castro

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http://www.thepajo.org/article.asp?issn=2666-4909;year=2020;volume=2;issue=1;spage=26;epage=26;aulast=Castro

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