Failure of Decidualization and Maternal Immune Tolerance Underlies Uterovascular Resistance in Intra Uterine Growth Restriction

Failure of Decidualization and Maternal Immune Tolerance Underlies Uterovascular Resistance in Intra Uterine Growth Restriction

Failure of uterine vascular transformation is associated with pregnancy complications including Intra Uterine Growth Restriction (IUGR). The decidua and its immune cell populations play a key role in the earliest stages of this process. Here we investigate the hypothesis that abnormal decidualizatio...

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Bibliographic Details
Main Authors: Caroline Dunk, Melissa Kwan, Aleah Hazan, Sierra Walker, Julie K. Wright, Lynda K. Harris, Rebecca Lee Jones, Sarah Keating, John C. P. Kingdom, Wendy Whittle, Cynthia Maxwell, Stephen J. Lye
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Endocrinology
Subjects:
IUGR
uterovascular transformation
decidua
EVT
immunology
T cells
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00160/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2019.00160/full

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