Whole transcriptome analysis reveals differential gene expression profile reflecting macrophage polarization in response to influenza A H5N1 virus infection

Whole transcriptome analysis reveals differential gene expression profile reflecting macrophage polarization in response to influenza A H5N1 virus infection

Abstract Background Avian influenza A H5N1 virus can cause lethal disease in humans. The virus can trigger severe pneumonia and lead to acute respiratory distress syndrome. Data from clinical, in vitro and in vivo suggest that virus-induced cytokine dysregulation could be a contributory factor to th...

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Bibliographic Details
Main Authors: Na Zhang, Yun-Juan Bao, Amy Hin-Yan Tong, Scott Zuyderduyn, Gary D. Bader, J. S. Malik Peiris, Si Lok, Suki Man-Yan Lee
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Medical Genomics
Subjects:
Influenza A virus
H5N1
Macrophage polarization
Transcriptomics
RNA-Seq
Online Access:http://link.springer.com/article/10.1186/s12920-018-0335-0

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http://link.springer.com/article/10.1186/s12920-018-0335-0

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