Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as a Model to Study Trypanosoma cruzi Infection

Summary: Chagas disease (ChD) is one of the most neglected tropical diseases, with cardiomyopathy being the main cause of death in Trypanosoma cruzi-infected patients. As the parasite actively replicates in cardiomyocytes (CMs), the heart remains a key target organ in the pathogenesis of ChD. Here w...

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Bibliographic Details
Main Authors: Adriana Bozzi, Nazish Sayed, Elena Matsa, Gabriele Sass, Evgenios Neofytou, Karl V. Clemons, Rodrigo Correa-Oliveira, David A. Stevens, Joseph C. Wu
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671119301390