Dynamic regulation of CTCF stability and sub-nuclear localization in response to stress.

The nuclear protein CCCTC-binding factor (CTCF) has diverse roles in chromatin architecture and gene regulation. Functionally, CTCF associates with thousands of genomic sites and interacts with proteins, such as cohesin, or non-coding RNAs to facilitate specific transcriptional programming. In this...

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Bibliographic Details
Main Authors: Bettina J Lehman, Fernando J Lopez-Diaz, Thom P Santisakultarm, Linjing Fang, Maxim N Shokhirev, Kenneth E Diffenderfer, Uri Manor, Beverly M Emerson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009277