Guanidinylation of Chitooligosaccharides Involving Internal Cyclization of the Guanidino Group on the Reducing End and Effect of Guanidinylation on Protein Binding Ability

In order to synthesize a promising material for developing a novel peptide/protein delivery system, guanidinylation of chitooligosaccharides with 1-amidinopyrazole hydrochloride was investigated herein. The production of guanidinylated chitooligosaccharides was demonstrated by infrared spectroscopy...

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Bibliographic Details
Main Authors: Hironori Izawa, Mizuki Kinai, Shinsuke Ifuku, Minoru Morimoto, Hiroyuki Saimoto
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/9/7/259