The dietary isothiocyanate sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancer

<p>Abstract</p> <p>Background</p> <p>Dietary or therapeutic interventions to counteract the loss of PTEN expression could contribute to the prevention of prostate carcinogenesis or reduce the rate of cancer progression. In this study, we investigate the interaction betw...

Full description

Bibliographic Details
Main Authors: Ball Richard Y, Melchini Antonietta, Doleman Joanne F, Spinks Caroline A, Traka Maria H, Mills Robert D, Mithen Richard F
Format: Article
Language:English
Published: BMC 2010-07-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/189