Direct and Indirect endocrine-mediated suppression of human endometrial CD8+T cell cytotoxicity

Abstract Regulation of endometrial (EM) CD8+T cells is essential for successful reproduction and protection against pathogens. Suppression of CD8+T cells is necessary for a tolerogenic environment that promotes implantation and pregnancy. However, the mechanisms regulating this process remain unclea...

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Bibliographic Details
Main Authors: Z. Shen, M. Rodriguez-Garcia, M. V. Patel, C. R. Wira
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81380-8