Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype

Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype

Abstract Background Genetic studies for complex diseases have predominantly discovered main effects at individual loci, but have not focused on genomic and environmental contexts important for a phenotype. Gene Set Enrichment Analysis (GSEA) aims to address this by identifying sets of genes or biolo...

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Main Authors: Vinicius Tragante, Johannes M. I. H. Gho, Janine F. Felix, Ramachandran S. Vasan, Nicholas L. Smith, Benjamin F. Voight, CHARGE Heart Failure Working Group, Colin Palmer, Pim van der Harst, Jason H. Moore, Folkert W. Asselbergs
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BioData Mining
Subjects:
Gene set enrichment analyses
Heart failure
Coronary artery disease
Online Access:http://link.springer.com/article/10.1186/s13040-017-0137-5

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http://link.springer.com/article/10.1186/s13040-017-0137-5

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