Crystal structure of diamondback moth ryanodine receptor Repeat34 domain reveals insect-specific phosphorylation sites

Abstract Background Ryanodine receptor (RyR), a calcium-release channel located in the sarcoplasmic reticulum membrane of muscles, is the target of insecticides used against a wide range of agricultural pests. Mammalian RyRs have been shown to be under the regulatory control of several kinases and p...

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Bibliographic Details
Main Authors: Tong Xu, Zhiguang Yuchi
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12915-019-0698-5