Nasal colonisation by Staphylococcus aureus depends upon clumping factor B binding to the squamous epithelial cell envelope protein loricrin.

Nasal colonisation by Staphylococcus aureus depends upon clumping factor B binding to the squamous epithelial cell envelope protein loricrin.

Staphylococcus aureus asymptomatically colonises the anterior nares, but the host and bacterial factors that facilitate colonisation remain incompletely understood. The S. aureus surface protein ClfB has been shown to mediate adherence to squamous epithelial cells in vitro and to promote nasal colon...

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Bibliographic Details
Main Authors: Michelle E Mulcahy, Joan A Geoghegan, Ian R Monk, Kate M O'Keeffe, Evelyn J Walsh, Timothy J Foster, Rachel M McLoughlin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3531522?pdf=render

Internet

http://europepmc.org/articles/PMC3531522?pdf=render

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