Assessing bacterial populations in the lung by replicate analysis of samples from the upper and lower respiratory tracts.

Microbes of the human respiratory tract are important in health and disease, but accurate sampling of the lung presents challenges. Lung microbes are commonly sampled by bronchoscopy, but to acquire samples the bronchoscope must pass through the upper respiratory tract, which is rich in microbes. He...

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Bibliographic Details
Main Authors: Emily S Charlson, Kyle Bittinger, Jun Chen, Joshua M Diamond, Hongzhe Li, Ronald G Collman, Frederic D Bushman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3435383?pdf=render