The deubiquitinating enzyme PSMD14 facilitates tumor growth and chemoresistance through stabilizing the ALK2 receptor in the initiation of BMP6 signaling pathway

Background: Although bone morphogenetic protein 6 (BMP6) signaling pathway has been implicated in many types of cancer, its role of tumorigenesis seems to be controversial and its ubiquitin-modifying mechanisms have not been fully addressed. Our study was designed to investigate how BMP6 signaling p...

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Bibliographic Details
Main Authors: Dongyeob Seo, Su Myung Jung, Jin Seok Park, Jaewon Lee, Jihoon Ha, Minbeom Kim, Seok Hee Park
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419307078