Metabolomic and Lipidomic Analysis of the Heart of Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-β Knock Out Mice on a High Fat Diet
The peroxisome proliferator-activated receptor-γ coactivators (PGC-1) are transcriptional coactivators with an important role in mitochondrial biogenesis and regulation of genes involved in the electron transport chain and oxidative phosphorylation in oxidative tissues including cardiac tissue. Thes...
Main Authors: | Gregor McCombie, Gema Medina-Gomez, Christopher J Lelliott, Antonio Vidal-Puig, Julian L Griffin |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2012-06-01
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Series: | Metabolites |
Subjects: | |
Online Access: | http://www.mdpi.com/2218-1989/2/2/366 |
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