High throughput sequencing of T-cell receptor repertoire using dry blood spots

High throughput sequencing of T-cell receptor repertoire using dry blood spots

Abstract Background Immunology research, particularly next generation sequencing (NGS) of the immune T-cell receptor β (TCRβ) repertoire, has advanced progression in several fields, including treatment of various cancers and autoimmune diseases. This study aimed to identify the TCR repertoires from...

Full description

Bibliographic Details
Main Authors: Shang-Gin Wu, Wenjing Pan, Hongna Liu, Miranda L. Byrne-Steele, Brittany Brown, Mollye Depinet, Xiaohong Hou, Jian Han, Song Li
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Journal of Translational Medicine
Subjects:
T cell receptor
TCR repertoire
CDR3
Dry blood spots
Next-generation sequence
Diversity
Online Access:http://link.springer.com/article/10.1186/s12967-019-1796-4

Internet

http://link.springer.com/article/10.1186/s12967-019-1796-4

Similar Items