My personal mutanome: a computational genomic medicine platform for searching network perturbing alleles linking genotype to phenotype

My personal mutanome: a computational genomic medicine platform for searching network perturbing alleles linking genotype to phenotype

Abstract Massive genome sequencing data have inspired new challenges in personalized treatments and facilitated oncological drug discovery. We present a comprehensive database, My Personal Mutanome (MPM), for accelerating the development of precision cancer medicine protocols. MPM contains 490,245 m...

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Bibliographic Details
Main Authors:	Yadi Zhou, Junfei Zhao, Jiansong Fang, William Martin, Lang Li, Ruth Nussinov, Timothy A. Chan, Charis Eng, Feixiong Cheng
Format:	Article
Language:	English
Published:	BMC 2021-01-01
Series:	Genome Biology
Subjects:	Mutanome Protein-protein interaction Edgetic Nodetic Somatic mutations Precision cancer medicine
Online Access:	https://doi.org/10.1186/s13059-021-02269-3

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