Serum microRNA-21 as a potential biomarker for response to hypomethylating agents in myelodysplastic syndromes.

Identification of biomarkers that predict responses to hypomethylating agents (HMAs) will allow optimal strategies for epigenetic therapy in myelodysplastic syndromes (MDS) to be established. Serum miR-21 was quantitatively measured in 58 MDS patients treated with HMAs and 14 healthy controls. Serum...

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Main Authors: Yundeok Kim, June-Won Cheong, Yeo-Kyeoung Kim, Ju-In Eom, Hoi-Kyung Jeung, Soo Jeong Kim, Dohyu Hwang, Jin Seok Kim, Hyeuong Joon Kim, Yoo Hong Min
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3913572?pdf=render