Longitudinal genome-wide DNA methylation analysis uncovers persistent early-life DNA methylation changes

Longitudinal genome-wide DNA methylation analysis uncovers persistent early-life DNA methylation changes

Abstract Background Early life is a period of drastic epigenetic remodeling in which the epigenome is especially sensitive to extrinsic and intrinsic influence. However, the epigenome-wide dynamics of the DNA methylation changes that occur during this period have not been sufficiently characterized...

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Bibliographic Details
Main Authors: Raúl F. Pérez, Pablo Santamarina, Juan Ramón Tejedor, Rocío G. Urdinguio, Julio Álvarez-Pitti, Pau Redon, Agustín F. Fernández, Mario F. Fraga, Empar Lurbe
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Journal of Translational Medicine
Subjects:
Epigenetics
DNA methylation
Histone modification
Aging
Newborn
Longitudinal
Online Access:http://link.springer.com/article/10.1186/s12967-018-1751-9

Internet

http://link.springer.com/article/10.1186/s12967-018-1751-9

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