Development and in vitro safety evaluation of pramipexole-loaded hollow mesoporous silica (HMS) particles

Development and in vitro safety evaluation of pramipexole-loaded hollow mesoporous silica (HMS) particles

In this study, spherical hollow mesoporous silica (HMS) particles with average size of 550 nm were loaded with dopamine-receptor agonist pramipexole, as a model drug. High drug loading (55%) was achieved by its incorporation in the reservoir structure of HMS. The newly developed drug-delivery system...

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Bibliographic Details
Main Authors: Borislav Tzankov, Christina Voycheva, Yordan Yordanov, Denitsa Aluani, Ivanka Spassova, Daniela Kovacheva, Nikolay Lambov, Virginia Tzankova
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
hms
pramipexole
sustained release
biocompatibility
antioxidant activity
Online Access:http://dx.doi.org/10.1080/13102818.2019.1649094

Internet

http://dx.doi.org/10.1080/13102818.2019.1649094

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