A Recombinant Fusion Construct between Human Serum Albumin and NTPDase CD39 Allows Anti-Inflammatory and Anti-Thrombotic Coating of Medical Devices

A Recombinant Fusion Construct between Human Serum Albumin and NTPDase CD39 Allows Anti-Inflammatory and Anti-Thrombotic Coating of Medical Devices

Medical devices directly exposed to blood are commonly used to treat cardiovascular diseases. However, these devices are associated with inflammatory reactions leading to delayed healing, rejection of foreign material or device-associated thrombus formation. We developed a novel recombinant fusion p...

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Bibliographic Details
Main Authors: Meike-Kristin Abraham, Elena Jost, Jan David Hohmann, Amy Kate Searle, Viktoria Bongcaron, Yuyang Song, Hans Peter Wendel, Karlheinz Peter, Stefanie Krajewski, Xiaowei Wang
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceutics
Subjects:
albumin
anti-thrombotic
CD39
coating of medical devices
stent coating
therapeutic fusion protein
Online Access:https://www.mdpi.com/1999-4923/13/9/1504

Internet

https://www.mdpi.com/1999-4923/13/9/1504

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