Comparison of family history and SNPs for predicting risk of complex disease.

The clinical utility of family history and genetic tests is generally well understood for simple Mendelian disorders and rare subforms of complex diseases that are directly attributable to highly penetrant genetic variants. However, little is presently known regarding the performance of these method...

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Bibliographic Details
Main Authors: Chuong B Do, David A Hinds, Uta Francke, Nicholas Eriksson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3469463?pdf=render