Multiple Stress Signals Induce p73β Accumulation

Although p73 is a structural and functional homologue of the tumor-suppressor gene p53, it is not mutated in many human cancers as p53. Besides, p73 was shown to be activated by only a subset of signals that activate p53, such as y-irradiation and cisplatin, but not by other common genotoxic stress...

Full description

Bibliographic Details
Main Authors: Kai Wei Lin, Shin Yuen Nam, Wen Hong Toh, Igbal Dulloo, Kanaga Sabapathy
Format: Article
Language:English
Published: Elsevier 2004-09-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558604800332