Vaccination with the Secreted Glycoprotein G of Herpes Simplex Virus 2 Induces Protective Immunity after Genital Infection

Herpes simplex virus 2 (HSV-2) infects the genital mucosa and establishes a life-long infection in sensory ganglia. After primary infection HSV-2 may reactivate causing recurrent genital ulcerations. HSV-2 infection is prevalent, and globally more than 400 million individuals are infected. As clinic...

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Bibliographic Details
Main Authors: Karin Önnheim, Maria Ekblad, Staffan Görander, Tomas Bergström, Jan-Åke Liljeqvist
Format: Article
Language:English
Published: MDPI AG 2016-04-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/8/4/110