The role of ion channels in the hypoxia-induced aggressiveness of glioblastoma

The role of ion channels in the hypoxia-induced aggressiveness of glioblastoma

The malignancy of glioblastoma multiform (GBM), the most common and aggressive form of human brain tumors, strongly correlates with the presence of hypoxic areas, but the mechanisms controlling the hypoxia-induced aggressiveness are still unclear. GBM cells express a number of ion channels whose act...

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Bibliographic Details
Main Authors: Luigi eSforna, Marta eCenciarini, Silvia eBelia, Maria Cristina D'Adamo, Mauro ePessia, Fabio eFranciolini, Luigi eCatacuzzeno
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Ion Channels
Cancer
hypoxia
aggressiveness
glioblastoma multiforme (GBM)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00467/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00467/full

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