Caspase-9 Activation and Caspase Cleavage of tau in the Alzheimer's Disease Brain

Caspase-9 Activation and Caspase Cleavage of tau in the Alzheimer's Disease Brain

Accumulating evidence supports a role for the activation of proteolytic enzymes, caspases, in the Alzheimer's disease (AD) brain. Neurons committed to apoptosis may do so through a mitochondrial pathway employing caspase-9 or through an alternative, receptor-mediated pathway involving caspase-8...

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Bibliographic Details
Main Authors: Troy T. Rohn, Robert A. Rissman, Michael C. Davis, Young Eun Kim, Carl W. Cotman, Elizabeth Head
Format: Article
Language:English
Published: Elsevier 2002-11-01
Series:Neurobiology of Disease
Subjects:
Alzheimer's disease
tau
caspase-9
caspase-3
neurofibrillary tangles
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996102905498

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http://www.sciencedirect.com/science/article/pii/S0969996102905498

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