Expanding the role of proteasome homeostasis in Parkinson’s disease: beyond protein breakdown

Abstract Proteasome is the principal hydrolytic machinery responsible for the great majority of protein degradation. The past three decades have testified prominent advances about proteasome involved in almost every aspect of biological processes. Nonetheless, inappropriate increase or decrease in p...

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Bibliographic Details
Main Authors: Mingxia Bi, Xixun Du, Qian Jiao, Xi Chen, Hong Jiang
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03441-0