Antitumor Activity of Extract From the Sporoderm-Breaking Spore of Ganoderma lucidum: Restoration on Exhausted Cytotoxic T Cell With Gut Microbiota Remodeling

Antitumor Activity of Extract From the Sporoderm-Breaking Spore of Ganoderma lucidum: Restoration on Exhausted Cytotoxic T Cell With Gut Microbiota Remodeling

As breast cancer is the leading cause of cancer-related deaths in women population worldwide, ongoing endeavor has been made for alternative regimens with improved efficacy but fewer adverse effects. Recently, active components from the spores of Ganoderma lucidum have attracted much attention for t...

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Bibliographic Details
Main Authors: Jiyan Su, Lu Su, Dan Li, Ou Shuai, Yifan Zhang, Huijia Liang, Chunwei Jiao, Zhanchi Xu, Yong Lai, Yizhen Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
spore of Ganoderma lucidum
cytotoxic T cells
exhaustion
immune checkpoints
gut microbiota
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01765/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01765/full

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