Exploring Alternative Radiolabeling Strategies for Sialic Acid-Binding Immunoglobulin-Like Lectin 9 Peptide: [68Ga]Ga- and [18F]AlF-NOTA-Siglec-9

Exploring Alternative Radiolabeling Strategies for Sialic Acid-Binding Immunoglobulin-Like Lectin 9 Peptide: [68Ga]Ga- and [18F]AlF-NOTA-Siglec-9

Amino acid residues 283–297 from sialic acid-binding immunoglobulin-like lectin 9 (Siglec-9) form a cyclic peptide ligand targeting vascular adhesion protein-1 (VAP-1). VAP-1 is associated with the transfer of leukocytes from blood to tissues upon inflammation. Therefore, analogs of Siglec-9 peptide...

Full description

Bibliographic Details
Main Authors: Olli Moisio, Riikka Siitonen, Heidi Liljenbäck, Elli Suomela, Sirpa Jalkanen, Xiang-Guo Li, Anne Roivainen
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Molecules
Subjects:
aluminum fluoride
fluorine-18
gallium-68
inflammation
positron emission tomography
Siglec-9
VAP-1
Online Access:http://www.mdpi.com/1420-3049/23/2/305

Internet

http://www.mdpi.com/1420-3049/23/2/305

Similar Items