Optimization and validation of a highly sensitive method for determining glyphosate in human urine by solid-phase extraction and liquid chromatography with tandem mass spectrometry: a methodological study

Optimization and validation of a highly sensitive method for determining glyphosate in human urine by solid-phase extraction and liquid chromatography with tandem mass spectrometry: a methodological study

Abstract Background Glyphosate and its salt formulations are nonselective herbicides that have been extensively used worldwide, both for residential and agricultural purposes. The possible carcinogenicity and teratogenicity of glyphosate remain to be elucidated. We developed a sensitive and high-thr...

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Bibliographic Details
Main Authors: Hiroshi Nomura, Risa Hamada, Isao Saito, Kunihiko Nakane, Ritsuko Sawa, Miwa Ukai, Eiji Shibata, Mitsuo Sato, Michihiro Kamijima, Jun Ueyama
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Environmental Health and Preventive Medicine
Subjects:
Biomonitoring
Glyphosate
Human urine
LC-MS/MS
Solid-phase extraction
Online Access:https://doi.org/10.1186/s12199-020-00918-w

Internet

https://doi.org/10.1186/s12199-020-00918-w

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