Historical Perspective of the G Protein-Coupled Receptor Kinase Family

Historical Perspective of the G Protein-Coupled Receptor Kinase Family

Agonist activation of G protein-coupled receptors promotes sequential interaction of the receptor with heterotrimeric G proteins, G protein-coupled receptor kinases (GRKs), and arrestins. GRKs play a central role in mediating the switch from G protein to arrestin interaction and thereby control proc...

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Bibliographic Details
Main Author: Jeffrey L. Benovic
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
arrestins
GPCR
GRK
phosphorylation
signaling
Online Access:https://www.mdpi.com/2073-4409/10/3/555

Internet

https://www.mdpi.com/2073-4409/10/3/555

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