Mucosal-Associated Invariant T Cells in Autoimmune Diseases

Mucosal-Associated Invariant T Cells in Autoimmune Diseases

Mucosal-associated invariant T (MAIT) cells are innate T cells restricted by MHC-related molecule 1 (MR1). MAIT cells express semi-invariant T-cell receptors TRAV1-2-TRAJ33/12/20 in humans and TRAV1-TRAJ33 in mice. MAIT cells recognize vitamin B2 biosynthesis derivatives presented by MR1. Similar to...

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Bibliographic Details
Main Authors: Asako Chiba, Goh Murayama, Sachiko Miyake
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
mucosal-associated invariant T cells
multiple sclerosis
systemic lupus erythematosus
inflammatory arthritis
inflammatory bowel diseases
diabetes
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01333/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01333/full

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