Sinusoidal Obstruction Syndrome Following Myeloablative Therapy and Tranexamic Acid Treatment for Hemorrhage in Two Patients with Neuroblastoma

Sinusoidal Obstruction Syndrome Following Myeloablative Therapy and Tranexamic Acid Treatment for Hemorrhage in Two Patients with Neuroblastoma

Adverse thromboembolic events following administration of the anti-fibrinolytic agent tranexamic acid (TA), used to prevent/treat excessive blood loss, are rare. We present the clinical course of two young patients (22 and 56 months) receiving busulfan/melphalan (Bu/Mel) high-dose chemotherapy with...

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Bibliographic Details
Main Authors: Felix Zirngibl, Carina Flemmig, Peter Lang, Annette Künkele, Angelika Eggert, Johannes H. Schulte, Hedwig E. Deubzer
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Children
Subjects:
pediatric hematopoietic stem cell transplantation
embryonal tumor
transplant-related complication
fibrinolysis inhibitor
thrombotic event
Online Access:https://www.mdpi.com/2227-9067/7/11/198

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https://www.mdpi.com/2227-9067/7/11/198

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