Structural differences between human proteins and aero- and microbial allergens define allergenicity.

The current paradigm suggests that structural homology of allergenic proteins to microbial (particularly helminths) or human proteins underlie their allergenic nature. To examine systematically the structural relationships among allergens and proteins of pathogens (helminths, protozoans, fungi and b...

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Bibliographic Details
Main Authors: Helton da Costa Santiago, Sasisekhar Bennuru, José M C Ribeiro, Thomas B Nutman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3399830?pdf=render