Astragaloside IV protects human trophoblast HTR8/SVneo cells from H2O2-Induced oxidative stress via Nrf2-Keap1-p62 feedback loop

Astragaloside IV protects human trophoblast HTR8/SVneo cells from H2O2-Induced oxidative stress via Nrf2-Keap1-p62 feedback loop

Preeclampsia is one of the serious complications of pregnancy and is the main cause of maternal death. Accumulation of trophoblastic reactive oxygen species (ROS) and placental dysfunction are the potential pathogenic bases of early-onset preeclampsia. Astragaloside IV (AS IV), one of the major and...

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Bibliographic Details
Main Authors: Fengge Wang, Miao Liu, Peng Lin, Jishui Wang, Lihua Zhang, Haiyan Zhang, Miaomiao Qu, Shuxiong Chen, Dongmei Man
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Journal of Functional Foods
Subjects:
Preeclampsia
astragaloside IV
Oxidative stress
Autophagy
Nrf2-Keap1-p62
Online Access:http://www.sciencedirect.com/science/article/pii/S175646462100270X

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http://www.sciencedirect.com/science/article/pii/S175646462100270X

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