NK cell dysfunction in chronic lymphocytic leukemia is associated with loss of the mature cells expressing inhibitory killer cell Ig-like receptors

NK cell dysfunction in chronic lymphocytic leukemia is associated with loss of the mature cells expressing inhibitory killer cell Ig-like receptors

A prospective analysis of natural killer (NK) cell phenotype and function was performed on fresh peripheral blood samples from untreated patients with B-cell chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). Compared to healthy controls, CD56dim NK cells in CLL patients display...

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Bibliographic Details
Main Authors: Alexander W. MacFarlane, Mowafaq Jillab, Mitchell R. Smith, R. Katherine Alpaugh, Marion E. Cole, Samuel Litwin, Michael M. Millenson, Tahseen Al-Saleem, Adam D. Cohen, Kerry S. Campbell
Format: Article
Language:English
Published: Taylor & Francis Group 2017-07-01
Series:OncoImmunology
Subjects:
chronic lymphocytic leukemia (cll)
killer cell ig-like receptors (kir)
natural killer (nk) cells
small lymphocytic lymphoma (sll)
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1330235

Internet

http://dx.doi.org/10.1080/2162402X.2017.1330235

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