High Circulating Caspase-Cleaved Keratin 18 Fragments (M30) Indicate Short-Term Mortality in Critically Ill Patients

High Circulating Caspase-Cleaved Keratin 18 Fragments (M30) Indicate Short-Term Mortality in Critically Ill Patients

Caspase-cleaved fragments of the intermediate filament protein keratin 18 (cytokeratin-18 (CK18)) can be detected in serum as M30 levels and may serve as a circulating biomarker indicating apoptosis of epithelial and parenchymal cells. In order to evaluate M30 as a biomarker in critical illness, we...

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Bibliographic Details
Main Authors: Alexander Koch, Eray Yagmur, Janine Linka, Fabienne Schumacher, Jan Bruensing, Lukas Buendgens, Ulf Herbers, Ger H. Koek, Ralf Weiskirchen, Christian Trautwein, Frank Tacke
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2018/8583121

Internet

http://dx.doi.org/10.1155/2018/8583121

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