Association test using Copy Number Profile Curves (CONCUR) enhances power in rare copy number variant analysis.

Association test using Copy Number Profile Curves (CONCUR) enhances power in rare copy number variant analysis.

Copy number variants (CNVs) are the gain or loss of DNA segments in the genome that can vary in dosage and length. CNVs comprise a large proportion of variation in human genomes and impact health conditions. To detect rare CNV associations, kernel-based methods have been shown to be a powerful tool...

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Bibliographic Details
Main Authors: Amanda Brucker, Wenbin Lu, Rachel Marceau West, Qi-You Yu, Chuhsing Kate Hsiao, Tzu-Hung Hsiao, Ching-Heng Lin, Patrik K E Magnusson, Patrick F Sullivan, Jin P Szatkiewicz, Tzu-Pin Lu, Jung-Ying Tzeng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-05-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007797

Internet

https://doi.org/10.1371/journal.pcbi.1007797

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