Potential Ago2/miR-3068-5p Cascades in the Nucleus Accumbens Contribute to Methamphetamine-Induced Locomotor Sensitization of Mice

Potential Ago2/miR-3068-5p Cascades in the Nucleus Accumbens Contribute to Methamphetamine-Induced Locomotor Sensitization of Mice

Dysregulation of microRNA (miRNA) biogenesis is involved in drug addiction. Argonaute2 (Ago2), a specific splicing protein involved in the generation of miRNA, was found to be dysregulated in the nucleus accumbens (NAc) of methamphetamine (METH)-sensitized mice in our previous study. Here, we determ...

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Bibliographic Details
Main Authors: Dan Liu, Min Liang, Li Zhu, Ting-ting Zhou, Yu Wang, Rui Wang, Fei-fei Wu, Eyleen L. K. Goh, Teng Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
Ago2
Grin1
locomotor sensitization
methamphetamine
miR-3068-5p
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.708034/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.708034/full

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