The presence of the DNA repair genes mutM, mutY, mutL and mutS is related to proteome size in bacterial genomes
DNA repair is expected to be a major modulator of underlying mutation rates, however the factors affecting the distribution and complexity of DNA repair pathways have not been determined. The Proteomic Constraint hypothesis proposes that mutation rates have evolved to be inversely proportional to th...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-02-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00003/full |