The presence of the DNA repair genes mutM, mutY, mutL and mutS is related to proteome size in bacterial genomes

DNA repair is expected to be a major modulator of underlying mutation rates, however the factors affecting the distribution and complexity of DNA repair pathways have not been determined. The Proteomic Constraint hypothesis proposes that mutation rates have evolved to be inversely proportional to th...

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Bibliographic Details
Main Authors: Aurian eGarcia-Gonzalez, Ruben eRivera-Rivera, Steven E Massey
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-02-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00003/full