Therapeutic use of dendritic cells to promote the extranodal priming of anti-tumor immunity

Ectopic lymphoid tissue, also known as tertiary lymphoid organs (TLO) develop adaptively within sites of chronic tissue inflammation, thereby allowing the host to efficiently crossprime specific immune effector cells within sites of disease. Recent evidence suggests that the presence of TLO in the t...

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Bibliographic Details
Main Authors: Lu eChen, Kellsye L. Fabian, Jennifer L. Taylor, Walter J. Storkus
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00388/full