Ursolic Acid Protected Lung of Rats From Damage Induced by Cigarette Smoke Extract

Ursolic Acid Protected Lung of Rats From Damage Induced by Cigarette Smoke Extract

Background: We found previously that ursolic acid (UA) administration could alleviate cigarette smoke-induced emphysema in rats partly through the unfolded protein response (UPR) PERK-CHOP and Nrf2 pathways, thus alleviating endoplasmic reticulum stress (ERS)-associated oxidative stress and cell apo...

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Bibliographic Details
Main Authors: Li Lin, Gang Hou, Dan Han, Jian Kang, Qiuyue Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Pharmacology
Subjects:
ursolic acid
cigarette smoke extract
chronic obstructive pulmonary disease
airway remodeling
endoplasmic reticulum stress
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00700/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00700/full

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