Genetic control of spontaneous arthritis in a four-way advanced intercross line.

Identifying the genetic basis of complex diseases, such as rheumatoid arthritis, remains a challenge that requires experimental models to reduce the genetic and environmental variability. Numerous loci for arthritis have been identified in induced animal models; however, few spontaneous models have...

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Bibliographic Details
Main Authors: Laura Mellado Ranea, Andreia de Castro Marques, Steffen Möller, Yask Gupta, Saleh M Ibrahim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3795728?pdf=render