Total DNA methylation in the brain in response to decitabine treatment in female rats

Hypomethylating agent decitabine is being used in the treatment of certain types of leukaemia in combination with other anticancer drugs. Aberrant DNA methylation has been suggested to occur in pathological states including depression. Scarce data in male rats suggest antidepressant effects of decit...

Full description

Bibliographic Details
Main Authors: Balagova L., Buzgoova K., Karailiev P., Jezova D.
Format: Article
Language:English
Published: Sciendo 2019-06-01
Series:European Pharmaceutical Journal
Subjects:
Online Access:https://doi.org/10.2478/afpuc-2019-0005