Total DNA methylation in the brain in response to decitabine treatment in female rats
Hypomethylating agent decitabine is being used in the treatment of certain types of leukaemia in combination with other anticancer drugs. Aberrant DNA methylation has been suggested to occur in pathological states including depression. Scarce data in male rats suggest antidepressant effects of decit...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2019-06-01
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Series: | European Pharmaceutical Journal |
Subjects: | |
Online Access: | https://doi.org/10.2478/afpuc-2019-0005 |