Impact of Genetic Variations and Epigenetic Mechanisms on the Risk of Obesity

Impact of Genetic Variations and Epigenetic Mechanisms on the Risk of Obesity

Rare genetic obesity disorders are characterized by mutations of genes strongly involved in the central or peripheral regulation of energy balance. These mutations are effective in causing the early onset of severe obesity and insatiable hunger (hyperphagia), suggesting that the genetic component ca...

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Bibliographic Details
Main Authors: Martina Chiurazzi, Mauro Cozzolino, Roberta Clara Orsini, Martina Di Maro, Matteo Nicola Dario Di Minno, Antonio Colantuoni
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
obesity
monogenic obesity
syndromic obesity
polygenic obesity
epigenetics
Online Access:https://www.mdpi.com/1422-0067/21/23/9035

Internet

https://www.mdpi.com/1422-0067/21/23/9035

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