Human iPSC-Derived Immature Astroglia Promote Oligodendrogenesis by Increasing TIMP-1 Secretion

Human iPSC-Derived Immature Astroglia Promote Oligodendrogenesis by Increasing TIMP-1 Secretion

Astrocytes, once considered passive support cells, are increasingly appreciated as dynamic regulators of neuronal development and function, in part via secreted factors. The extent to which they similarly regulate oligodendrocytes or proliferation and differentiation of oligodendrocyte progenitor ce...

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Bibliographic Details
Main Authors: Peng Jiang, Chen Chen, Xiao-Bo Liu, David E. Pleasure, Ying Liu, Wenbin Deng
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Cell Reports
Subjects:
human induced pluripotent stem cells
immature astrocytes
periventricular leukomalacia
oligodendrocytes
myelination
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716304107

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http://www.sciencedirect.com/science/article/pii/S2211124716304107

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